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Updated: Dec 13, 2025
A Single Cell Dissociation Approach for Molecular Analysis of Urinary Bladder in the Mouse Following Spinal Cord Injury
Published on: June 17, 2020
Inflammatory myofibroblastic bladder tumor with divergent behavior in a patient with spinal cord injury
Ichiro Tsuboi1,2,3, Yuki Maruyama1,3, Takuya Sadahira1,3
1Department of Urology Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences Kita-ku Okayama Japan.
Introduction:
An inflammatory myofibroblastic tumor of the bladder is rare. Some urothelial carcinoma with sarcomatoid changes may mimic an inflammatory myofibroblastic tumor.
Case Presentation:
A 76-year-old man with indwelling urinary catheters because of a spinal cord injury presented with gross hematuria. Transurethral electrocoagulation and a resection were performed. A T2-weighted magnetic resonance imaging showed a tumor and hematoma in the bladder diverticulum that pathologically resembled an inflammatory myofibroblastic tumor. This lesion was then removed en bloc by partial cystectomy. Histology showed a squamous cell carcinoma with sarcomatoid changes. After 4 months, a computed tomography showed the lesion had expanded outside the skin adjacent to the bladder.
Conclusion:
Some cases of inflammatory myofibroblastic tumors have a malignant course. Urologists therefore need to be aware of the possibility of rare cases of malignant bladder myofibroblasts.
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