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Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
Published on: July 18, 2017
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Renal failure due to encrusted cystitis and pyelitis
Katsuhiro Ito1, Toshifumi Takahashi1, Toru Kanno1
1Department of Urology Ijinkai Takeda General Hospital Kyoto Japan.
IJU Case Reports
|August 4, 2020
Summary
Encrusted cystitis and pyelitis, a rare infection causing urinary tract calcification, can progress to kidney damage if diagnosis is delayed. Prompt treatment with antibiotics and bladder irrigation can lead to regression.
Area of Science:
- Urology
- Infectious Diseases
- Nephrology
Background:
- Encrusted cystitis and pyelitis are uncommon urinary tract infections characterized by calcification within the urinary collecting system.
- This case highlights the potential for rapid progression of encrusted cystitis to pyelitis and renal failure.
Observation:
- A 73-year-old male with granulomatosis with polyangiitis presented with hematuria and dysuria.
- Initial cystoscopy revealed bladder wall calcification, misdiagnosed as a bladder stone.
- Over a month, calcification spread to the renal pelvis, causing bilateral renal failure.
Findings:
- The patient received bilateral nephrostomy, bladder irrigation with Solita T1, and intravenous vancomycin.
- Significant regression of calcification was observed after 4 weeks of treatment.
- Alkaline urine and urothelial calcification are key indicators for suspecting encrusted cystitis and pyelitis.
Implications:
- Early diagnosis and intervention are crucial to prevent severe renal complications.
- Treatment strategies should encompass antibiotics, urine drainage, and chemolysis via bladder irrigation.
- This case underscores the importance of considering rare infections in patients with atypical urinary symptoms.
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