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Updated: Dec 13, 2025
Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model
Published on: August 11, 2023
Risk Factors for Stroke Based on the National Health and Nutrition Examination Survey
1Xingmin Liang: Department of Emergency, Panyu Central Hospital, Guangzhou, Guangdong 510006, P.R. China, Tel: +86 020-3485800,
Objectives:
To explore the risk factors for stroke by using National Health and Nutrition Examination Survey (NHANES).
Methods:
A total of 19384 cases from the NHANES database during 2005 to 2016 were included in this study, of which 661 were stroke patients, with a weighted prevalence of 2.60%. Univariate and multivariate logistic regression analysis was used to analyze possible risk factors for stroke.
Results:
The risk of stroke was 1.839 times higher in subjects with diabetes than in those without diabetes, P<0.001. An average increase of 1 ug/dL in blood lead was associated with a 1.082-fold increase in stroke risk, P<0.001. Subjects with mild-, moderate-, and moderately severe or severe depression had a 1.567-fold, 1.836-fold, and 3.279-fold higher risk than those without depression respectively, P<0.001. The risk of stroke in subjects with sleep disorders was 1.622 times higher than those without sleep disorders, P<0.001.
Conclusions:
Patients with diabetes, lower household income (<$2000), PHQ-9 depression score (5-27), trouble sleep, older age and higher concentration of blood lead are associated with a higher risk of stroke.
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