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Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms
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Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms

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Relevance of Higher-Order Epistasis in Drug Resistance

Elena R Lozovsky1, Rachel F Daniels2, Gavin D Heffernan3

  • 1Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA.

Molecular Biology and Evolution
|August 4, 2020
PubMed

Keywords:
Plasmodium falciparumadaptive topographydihydrofolate reductasedrug developmentepistasistriazine antifolates

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