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COVID-19 in patients with HIV-1 infection: a single-centre experience in northern Italy

Leonardo Calza1, Isabella Bon2, Marina Tadolini3

  • 1Department of Medical and Surgical Sciences, Unit of Infectious Diseases, "Alma Mater Studiorum" University of Bologna, S. Orsola-Malpighi Hospital, via G. Massarenti 11 - I-40138, Bologna, Italy. leonardo.calza@unibo.it.

Infection
|August 5, 2020
PubMed

Insights

Coronavirus Disease 2019 (COVID-19) in people with human immunodeficiency virus (HIV) infection presented similarly to the general population. This case series found no intensive care unit admissions or deaths among HIV-positive patients with COVID-19.

Area of Science:

  • Infectious Diseases
  • Virology
  • Public Health

Background:

  • The Coronavirus Disease 2019 (COVID-19) pandemic rapidly impacted Europe starting in early 2020.
  • Limited data existed on COVID-19 characteristics in patients with human immunodeficiency virus (HIV) infection.

Purpose of the Study:

  • To describe the clinical presentation and outcomes of COVID-19 in patients with HIV infection.
  • To compare COVID-19 characteristics in HIV-infected individuals to the general population.

Main Methods:

  • A case series was conducted at S.Orsola Hospital in Bologna, Italy.
  • Data were collected for HIV-infected patients diagnosed with COVID-19 between March and April 2020.

Main Results:

  • Twenty-six HIV-infected patients with COVID-19 were included.
  • The median age was 54 years, with 19 males. 73% had comorbidities.
  • Only 5 patients developed interstitial pneumonia; none required intensive care or resulted in death.

Conclusions:

  • COVID-19 in HIV-infected individuals exhibited a clinical presentation comparable to the general population.
  • Chronic comorbidities were frequently observed in this patient group.
Abstract

Keywords:
ComorbidityCoronavirusHIVPneumoniaProtease inhibitors

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