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BMI is Associated with Coronavirus Disease 2019 Intensive Care Unit Admission in African Americans
Ala L Alkhatib1, Jonah Kreniske2, Jerry S Zifodya1
1Department of Medicine, Section of Pulmonary Diseases, Critical Care and Environmental Medicine, Health Science Center, Tulane University, New Orleans, Louisiana, USA.
Insights
African Americans with COVID-19 face higher risks for severe disease. Key risk factors identified include advanced age, higher body mass index (BMI), and pre-existing lung conditions, necessitating targeted interventions.
Area of Science:
- Medical Research
- Epidemiology
- Public Health
Background:
- The COVID-19 pandemic has disproportionately affected African American communities.
- Understanding specific risk factors within this demographic is crucial for equitable healthcare responses.
Purpose of the Study:
- To identify risk factors associated with severe Coronavirus disease 2019 (COVID-19) in African American patients.
- To inform targeted clinical care strategies for this population.
Main Methods:
- A retrospective cross-sectional analysis was conducted.
- Data from 158 African American COVID-19 patients treated at a single tertiary center were analyzed.
- Severe disease was defined as requiring intensive care unit (ICU) admission.
Main Results:
- Older age (mean 62 vs. 55 years) and higher body mass index (BMI) (mean 36.5 vs. 31.9 kg/m² ) were significantly associated with ICU admission.
- Adjusted analysis revealed age (aOR: 1.073), BMI (aOR: 1.115), and lung disease (aOR: 3.097) as key predictors of severe COVID-19.
- The study included 158 patients, with 61% being women and a mean age of 57 years.
Conclusions:
- Age, BMI, and lung disease are significant risk factors for severe COVID-19 in African Americans.
- Further research is essential to optimize clinical care and ensure health equity for this population.
- Targeted interventions are critical for an equitable COVID-19 response.
Objective:
Coronavirus disease 2019 (COVID-19) has disproportionately impacted the African American community. This study aims to identify the risk factors for severe COVID-19 disease in African American patients.
Methods:
This was a retrospective cross-sectional analysis of African American patients with COVID-19 treated between March 12 and April 9, 2020, at a single tertiary center. The primary outcome of interest was severe disease defined as those requiring intensive care unit (ICU) admission.
Results:
The study included 158 consecutive patients. The mean age was 57 years, and 61% were women. The mean (SD) of BMI was 33.2 (8.6) kg/m2 . Overall, patients admitted to the ICU were older (62 vs. 55 years, P = 0.003) and had higher BMI (36.5 kg/m2 vs. 31.9 kg/m2 , P = 0.002). In unadjusted and adjusted analysis, the factors most associated with ICU admission in this sample were age (adjusted odds ratio [aOR]: 1.073; 95% CI: 1.033-1.114), BMI (aOR: 1.115; 95% CI: 1.052-1.182), and lung disease (aOR: 3.097; 95% CI: 1.137-8.437).
Conclusions:
This study identified risk factors for severe disease in COVID-19, specifically in an African American population. Further inclusive research aimed at optimizing clinical care relevant to the African American population is critical to ensure an equitable response to COVID-19.
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