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Updated: Dec 13, 2025

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
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Published on: October 20, 2016

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Biventricular strain by speckle tracking echocardiography in COVID-19: findings and possible prognostic implications

Parasuram Krishnamoorthy1, Lori B Croft1, Richard Ro1

  • 1The Zena & Michael A Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, NY, USA.

Future Cardiology
|August 5, 2020
PubMed

Insights

COVID-19 infection impacts the heart. Reduced right ventricular strain in patients with poor outcomes suggests it may aid in risk stratification for cardiovascular complications.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Medical Imaging

Background:

  • COVID-19 infection poses significant risks to the cardiovascular system.
  • Transthoracic echocardiography is a valuable tool for diagnosing and managing cardiovascular conditions.
  • Myocardial strain analysis offers detailed insights into cardiac function.

Purpose of the Study:

  • To investigate biventricular myocardial strain patterns in patients with COVID-19.
  • To assess the diagnostic and prognostic utility of strain measurements in COVID-19 patients.
  • To correlate strain parameters with patient outcomes, including discharge, intubation, or death.

Main Methods:

  • Biventricular strain measurements were conducted on 12 patients diagnosed with COVID-19.
  • Patients were categorized into two groups: those discharged and those requiring intubation and/or succumbing to the infection.
  • Comparative analysis of strain parameters between the two outcome groups was performed.

Main Results:

  • Five patients experienced poor outcomes (intubation/death), while seven were discharged.
  • Significantly decreased right ventricular strain parameters were observed in patients with poor outcomes.
  • Left ventricular strain was reduced in both groups, but this finding did not reach statistical significance.

Conclusions:

  • Right ventricular strain reduction is associated with adverse outcomes in COVID-19 patients.
  • Left ventricular strain reduction occurred irrespective of patient outcome.
  • Right ventricular strain may serve as a crucial indicator for risk stratification and prognosis in COVID-19 cardiovascular complications.

Keywords:
COVID-19 infectioncoronavirusmyocardial strain imagingspeckle tracking echocardiographytransthoracic echocardiography

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