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Updated: Dec 13, 2025

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
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Human virus detection with graphene-based materials.

Eleni Vermisoglou1, David Panáček2, Kolleboyina Jayaramulu3

  • 1Regional Centre of Advanced Technologies and Materials (RCPTM), Faculty of Science, Palacký University Olomouc, Czech Republic.

Biosensors & Bioelectronics
|August 5, 2020
PubMed
Summary
This summary is machine-generated.

Graphene-based biosensors offer rapid, sensitive, and selective detection of various viruses, crucial for disease monitoring and treatment. Their unique properties enable the development of advanced, miniaturized virus detection systems.

Keywords:
BiosensorGrapheneNanocompositeSARS-CoV-2Virus

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Area of Science:

  • Nanomaterials Science
  • Biosensor Technology
  • Virology

Background:

  • The COVID-19 pandemic underscored the need for rapid, sensitive, and selective virus detection methods.
  • Early virus detection is critical for timely treatment, reduced morbidity, and effective disease management.
  • Graphene's unique properties make it a promising material for advanced biosensor development.

Purpose of the Study:

  • To review various graphene-based sensor types for virus detection.
  • To discuss strategies for enhancing graphene sensor sensitivity and selectivity.
  • To summarize current applications of graphene biosensors for diverse viral pathogens.

Main Methods:

  • Review of photoluminescence, colorimetric, and surface plasmon resonance biosensors.
  • Discussion of electrochemical detection strategies based on DNA hybridization and antigen-antibody interactions.
  • Analysis of graphene functionalization and hybrid material approaches.

Main Results:

  • Graphene-based sensors demonstrate high sensitivity and selectivity for detecting multiple viruses, including SARS-CoV-2, influenza, and HIV.
  • Functionalization and hybrid structures enhance graphene's optical and electrical properties for improved detection.
  • Graphene nanomaterials are suitable for engineering and miniaturizing virus biosensors.

Conclusions:

  • Graphene-based biosensors are highly effective for rapid and accurate virus detection.
  • The tunable properties of graphene are ideal for developing next-generation, miniaturized diagnostic tools.
  • Continued research in graphene functionalization will further advance virus sensing capabilities.