Jove
Visualize
Contact Us

Related Concept Videos

Drug Therapy01:28

Drug Therapy

185
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
185
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

361
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
361
Antipsychotic Drugs: Typical and Atypical Agents01:21

Antipsychotic Drugs: Typical and Atypical Agents

600
Antipsychotic drugs are classified into first-generation (typical) drugs including phenothiazines; and second-generation (atypical) drugs. Chlorpromazine hydrochloride (Thorazine), a phenothiazine derivative, broadly impacts the central, autonomic, and endocrine systems. This drug, along with typical agents like haloperidol (Haldol), primarily works by antagonizing D2 receptors, thus reducing dopaminergic neurotransmission. However, typical antipsychotics can cause side effects such as sedation...
600
Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

689
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
689
Antipsychotic Drugs: Therapeutic Uses and Side Effects01:21

Antipsychotic Drugs: Therapeutic Uses and Side Effects

588
Antipsychotic drugs primarily block dopamine and serotonin receptors and cholinergic, adrenergic, and histaminergic receptors, thereby reducing hallucinations and delusions in conditions like schizophrenia. However, they can trigger unwanted extrapyramidal effects such as dystonias, Parkinson-like symptoms, and tardive dyskinesia.
Despite these side effects, antipsychotics are used therapeutically for various purposes, including managing schizophrenia, preventing nausea and vomiting, curbing...
588
Antidepressant Drugs: MAOIs and Other Agents01:23

Antidepressant Drugs: MAOIs and Other Agents

666
Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
666

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management of Schizophrenia Spectrum Disorders in the Outpatient Setting: A Quality Improvement Project.

Journal of doctoral nursing practice·2020
Same author

Electronic Nicotine Delivery Systems (ENDS): What Nurses Need to Know.

Journal of the American Psychiatric Nurses Association·2017
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Dec 13, 2025

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients
11:05

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients

Published on: February 6, 2021

16.4K

Adherence to Clinical Practice Guidelines When Prescribing Second-Generation Antipsychotics.

Leigh Powers1

  • 1East Tennessee State University powerslg@etsu.edu.

Journal of Doctoral Nursing Practice
|August 6, 2020
PubMed
Summary
This summary is machine-generated.

Adherence to monitoring guidelines for second-generation antipsychotics (SGAs) was low, with less than 30% of patients receiving initial blood glucose and lipid tests. This indicates a need for improved mental health care quality and patient monitoring.

Keywords:
careevidence-based practicemonitoringqualitysecond-generation antipsychotics

More Related Videos

Development of a Virtual Reality Assessment of Everyday Living Skills
10:32

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

18.9K
An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
19:57

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

Published on: March 30, 2014

19.0K

Related Experiment Videos

Last Updated: Dec 13, 2025

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients
11:05

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients

Published on: February 6, 2021

16.4K
Development of a Virtual Reality Assessment of Everyday Living Skills
10:32

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

18.9K
An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
19:57

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

Published on: March 30, 2014

19.0K

Area of Science:

  • Psychiatry
  • Clinical Pharmacy
  • Public Health

Background:

  • Second-generation antipsychotics (SGAs) are widely used for mental illness treatment.
  • Established guidelines recommend regular monitoring for adverse effects of SGAs.
  • Assessing adherence to these guidelines is crucial for ensuring quality patient care.

Purpose of the Study:

  • To evaluate adherence to side effect monitoring guidelines for SGAs.
  • To assess the quality of care for mental illness patients at a community mental health center.
  • To determine monitoring rates approximately 10 years post-guideline publication.

Main Methods:

  • Retrospective chart review at an urban community mental health center in the Southeast US.
  • Analysis of adherence rates for fasting blood glucose (FBG) and fasting lipid profile (FLP) monitoring.
  • Data collection at baseline, 3 months, and 1 year.

Main Results:

  • Initial combined FBG and FLP collection was only 30%.
  • Monitoring rates decreased to 20% at 3 months and 14% at 1 year.
  • Significant gaps in guideline adherence were identified.

Conclusions:

  • Current adherence to SGA side effect monitoring guidelines is suboptimal.
  • There is a clear need for practice improvements in mental health centers.
  • Enhanced monitoring is essential to improve the quality of care for patients on SGAs.