Related Experiment Video
Updated: Dec 13, 2025

High-Throughput Metabolic Profiling for Model Refinements of Microalgae
Published on: December 4, 2021
Moonlighting Proteins in the Fuzzy Logic of Cellular Metabolism
Haipeng Liu1, Constance J Jeffery2
1Center for Biomolecular Sciences, College of Pharmacy, University of Illinois at Chicago, 900 South Ashland Avenue, Chicago, IL 60607, USA.
Abstract:
The numerous interconnected biochemical pathways that make up the metabolism of a living cell comprise a fuzzy logic system because of its high level of complexity and our inability to fully understand, predict, and model the many activities, how they interact, and their regulation. Each cell contains thousands of proteins with changing levels of expression, levels of activity, and patterns of interactions. Adding more layers of complexity is the number of proteins that have multiple functions. Moonlighting proteins include a wide variety of proteins where two or more functions are performed by one polypeptide chain. In this article, we discuss examples of proteins with variable functions that contribute to the fuzziness of cellular metabolism.
Related Concept Videos
Regulation of Metabolism
Other Glycolytic Pathways
Introduction to Metabolism
Translational Regulation
Lipid Catabolism
Overview of Metabolism
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...

