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Topical agents: a thoughtful choice for multimodal analgesia
Eunjoo Choi1, Francis Sahngun Nahm1,2, Woong Ki Han1
1Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Korean Journal of Anesthesiology
|August 6, 2020
Summary
Topical analgesics offer effective pain relief with fewer risks than systemic drugs. This review covers their mechanisms and new options for multimodal pain management.
Area of Science:
- Pharmacology
- Pain Management
- Dermatology
Background:
- Topical pain relief has a long history, with some ancient ingredients still in use.
- Concerns about systemic nonsteroidal anti-inflammatory drugs (NSAIDs) and opioids drive interest in topical alternatives.
- Topical analgesics are increasingly recognized for their efficacy and safety in pain control.
Purpose of the Study:
- To review essential aspects of topical analgesics for physicians.
- To discuss the mechanisms of common topical pain relief medications.
- To introduce novel and experimental topical agents for pain management.
Main Methods:
- Literature review of historical and current topical analgesic substances.
- Analysis of mechanisms of action for popular topical analgesics.
- Inclusion of recently developed and experimental topical medications.
Main Results:
- Topical analgesics provide a viable alternative for pain management.
- Evidence supports the safety and efficacy of topical agents.
- These agents are valuable components of multimodal analgesia.
Conclusions:
- Topical analgesics are crucial for modern pain management strategies.
- Physicians should consider topical options as part of multimodal analgesia.
- Understanding mechanisms and new developments enhances clinical practice.
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