How IQ depends on the running mode of brain network?

Increasing evidence has shown that intelligence quotient (IQ) depends not only on the aspect of phenomenology such as the size of brain and sexuality but also on the topology of the brain network. We here try to get a deeper understanding by asking how the running mode of the brain network influences IQ. We introduce a parameter α to represent the trade-off between wiring cost and processing efficiency and figure out the optimal value of α by the approach of network reconstruction. A negative correlation between optimal index α and IQ is revealed. To further find out the mechanism for the functional difference between males and females, we move to the local level of brain regions and study the relationship between regional optimal α and IQ. We find that the Pearson coefficients of males are significantly different from that of females, including both global and regional levels. These findings show that the functional differences between individuals, including the differences between males and females, are closely related to the different running modes of their brain networks.