Depressive symptoms, memory complaints, and memory test performance

The impact of emotional factors on subjective cognitive complaints and memory test performance has been a topic of extensive research, produced conflicting results. Investigators typically used self-report inventories that lack measures of response bias. Studies have also neglected to use performance validity tests (PVTs) to screen participants for incomplete effort. In the present study, 27% of the original sample of non-litigating outpatient referrals (N = 416) failed to meet self-report and performance validity criteria. Remaining participants (N = 226) were classified into high and low depression groups using their median score (66 T) on Scale D (Depression) of the MMPI-2. "High depression" subjects scored over 65 T on the D scale (MN = 77 T). "Low depression" subjects scored below 66 T (MN = 56 T). Test performances were compared across WAIS-IV Digit Span, Wechsler Memory Scale IV Logical Memory and Visual Reproduction subtests, and the Miami Selective Learning Test. High and low depressive groups exhibited no significant mean score differences on any memory measures. Cognitive Complaints on the Cognitive Difficulties Scale (CDS) were associated with level of depressive symptoms (r(226) =.42, p <.001). Complaints were predictive of delayed (30 min) list recall (r(224) =.19, p =.006, but were not related to eight other memory measures. Results suggest that, in general, depression severity is predictive of cognitive complaints yet has little, if any, relation to memory test performance.