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Machine Learning-Based Cough Tone Classification: Diagnostic Exploration of Chronic Obstructive Pulmonary Disease and Respiratory Tract Infections

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Published on: September 19, 2025

Persistent cough: An unexpected diagnosis.

Suman K Panda¹, Bhagyalakshmi Satyanarayan¹, Satish K Prasad¹

¹Department of Medicine, Tata Main Hospital, Jamshedpur, Jharkhand, India.

Journal of Family Medicine and Primary Care

|August 6, 2020

Summary

This summary is machine-generated.

Esophageal squamous cell carcinoma (ESCC) is a common cancer. This case highlights how persistent respiratory symptoms can indicate advanced esophageal malignancy, emphasizing the need for thorough investigation.

Keywords:

Chronic cough squamous cell carcinoma of esophagus

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Area of Science:

Oncology
Gastroenterology
Pulmonology

Background:

Esophageal cancer is a significant global health concern, ranking eighth in incidence and sixth in mortality.
Esophageal squamous cell carcinoma (ESCC) comprises the vast majority (70%-90%) of esophageal malignancies worldwide.

Observation:

A 54-year-old female presented with recurrent dry cough and respiratory issues.
Computed tomography (CT) scans revealed esophageal wall thickening, mediastinal lymphadenopathy, and right lobe atelectasis, suggesting malignancy.
Endoscopy identified a circumferential esophageal growth.

Findings:

Histopathological examination confirmed moderately differentiated squamous cell carcinoma of the esophagus.
The patient's respiratory symptoms were attributed to the advanced esophageal malignancy.

Implications:

This case underscores the importance of considering esophageal cancer in patients with persistent, unexplained respiratory symptoms.
Early and accurate diagnosis of ESCC is crucial for timely intervention and improved patient outcomes.
Multidisciplinary evaluation is essential for managing complex cases of esophageal cancer presenting with atypical symptoms.