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Review: An insight into coronaviruses: Challenges, security and scope
Niyati Shah1, Vipul Davariya2, Sanjeev K Gupta1
1Computational Materials and Nanoscience Group, Department of Physics and Electronics, St. Xavier's College, Ahmedabad, India.
Reviews in Medical Virology
|August 6, 2020
Summary
Researchers reviewed potential drugs and vaccines for SARS-CoV-2, the virus causing the COVID-19 pandemic. This review examines scientific therapies, drug mechanisms, clinical trial efficiency, and side effects to combat the novel coronavirus.
Area of Science:
- Virology
- Infectious Diseases
- Pharmacology
Background:
- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerged in late 2019, causing a global pandemic.
- No specific cures or vaccines were initially available for this novel coronavirus.
- Extensive global research is underway to develop effective treatments and preventative measures.
Purpose of the Study:
- To review existing and potential drugs and vaccines against SARS-CoV-2.
- To analyze the efficacy and mechanisms of various scientific therapies.
- To assess the outcomes and side effects observed in clinical trials for COVID-19 treatments.
Main Methods:
- Systematic review of scientific literature and clinical trial data.
- Analysis of drug mechanisms and therapeutic pathways.
- Evaluation of drug efficiency, safety profiles, and side effects.
Main Results:
- Identification of several promising drug candidates and vaccine platforms.
- Detailed examination of the pharmacological actions of potential treatments.
- Summary of clinical trial findings regarding efficacy and adverse events.
Conclusions:
- The review highlights key therapeutic strategies and vaccine candidates for SARS-CoV-2.
- Understanding drug mechanisms and trial results is crucial for developing effective COVID-19 treatments.
- Ongoing research is vital for controlling the pandemic and mitigating its impact.
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