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Clinical Course and Mortality of Stroke Patients With Coronavirus Disease 2019 in Wuhan, China

Lijuan Zhang1, Wenwu Sun1, Yujun Wang1

  • 1Intensive Care Unit (L.Z., W.S., Y.W., X.W., Y.L., D.L., L.Y.), the Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, China.

Stroke
|August 7, 2020
PubMed

Insights

Patients with preexisting stroke who contract COVID-19 face a higher risk of critical illness and death. This highlights the urgent need for preventive measures to protect stroke patients during the COVID-19 pandemic.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Public Health

Background:

  • The impact of the COVID-19 pandemic on patients with pre-existing stroke remains understudied.
  • Understanding clinical outcomes and risk factors is crucial for managing this vulnerable population.

Purpose of the Study:

  • To investigate the clinical course of COVID-19 in patients with pre-existing stroke.
  • To identify risk factors associated with mortality in these patients.

Main Methods:

  • A cohort of 651 adult COVID-19 inpatients was analyzed.
  • Data included demographics, comorbidities, clinical presentation, and outcomes.
  • Cox regression models assessed mortality risk factors in stroke patients.

Main Results:

  • COVID-19 patients with stroke were older, more likely male, and had more comorbidities.
  • Stroke patients exhibited greater illness severity, longer hospital stays, and higher costs.
  • Preexisting stroke was associated with increased risk of critical pneumonia and mortality.

Conclusions:

  • Patients with stroke are at a higher risk of death when infected with SARS-CoV-2.
  • Implementing preventive measures is essential to protect stroke patients during the COVID-19 crisis.
Abstract

Keywords:
comorbiditiescoronavirus diseasedemographymortalitysevere acute respiratory syndrome

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