Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Complete mitochondrial genomes of four pharyngodonid nematodes reveal extensive gene order rearrangement.

Journal of helminthology·2026
Same author

Evaluating the morality of violence against robots.

Scientific reports·2025
Same author

Considering late effects costs in radiotherapy funding.

The British journal of radiology·2025
Same author

Radiotherapy commissioning and tariff-how can we deliver advanced, innovative, and personalised radiotherapy?

The British journal of radiology·2025
Same author

Sustainable capital funding for modern and innovative radiotherapy services.

The British journal of radiology·2025
Same author

A first report of Pseudosuccinea columella (Say, 1817), an alien intermediate host for liver fluke, in Malawi.

Parasites & vectors·2024

Related Experiment Video

Updated: Dec 12, 2025

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

16.1K

BrachyView: development of an algorithm for real-time automatic LDR brachytherapy seed detection.

T Brennen1,2, L Galli3, D L Cutajar1,4

  • 1Centre for Medical Radiation Physics, University of Wollongong, Australia.

Physics in Medicine and Biology
|August 7, 2020
PubMed
Summary

This study introduces an automated algorithm for identifying brachytherapy seed positions during prostate cancer treatment. The system achieves high accuracy and speed, enabling real-time intraoperative dosimetry for improved patient outcomes.

More Related Videos

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

7.6K
Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
07:57

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Published on: March 24, 2022

3.0K

Related Experiment Videos

Last Updated: Dec 12, 2025

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

16.1K
Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

7.6K
Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
07:57

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Published on: March 24, 2022

3.0K

Area of Science:

  • Medical Imaging
  • Radiation Oncology
  • Computational Imaging

Background:

  • Low dose rate (LDR) prostate brachytherapy requires accurate seed placement for effective treatment.
  • Intraoperative dosimetry is crucial for real-time monitoring and adjustment of radiation delivery.
  • Current methods for seed localization can be time-consuming and may lack real-time capabilities.

Purpose of the Study:

  • To develop and validate a fully automatic algorithm for seed centre of mass identification and 3D position reconstruction.
  • To enable real-time intraoperative dosimetry for LDR prostate brachytherapy using the BrachyView system.
  • To improve the accuracy and efficiency of seed localization in brachytherapy.

Main Methods:

  • Development of an algorithm utilizing Speeded Up Robust Features (SURF) for detecting 2D seed projections.
  • Implementation of automatic frame alignment and subtraction procedures to remove background noise and artifacts.
  • Testing with datasets of 30, 96, and 98 I-125 seeds implanted in a prostate gel phantom.

Main Results:

  • The algorithm achieved 97% seed detection and 97% seed matching accuracy.
  • Demonstrated an average computation time of 2.75 seconds per image.
  • Improved reconstruction accuracy by 22.87% for the 98-seed dataset and reduced false positives by 99.9%.

Conclusions:

  • The developed algorithm enables robust and accurate identification of brachytherapy seeds.
  • The system facilitates real-time intraoperative dosimetry, enhancing the precision of LDR prostate brachytherapy.
  • This advancement supports the BrachyView system's potential as a valuable tool in radiation oncology.