Vitamin D for inflammation biomarkers in coronary artery disease: A protocol for systematic review and meta-analysis

Yiru Wang1, Yifan Zhang1, Jing Wei2

  • 1Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine.

Medicine
|August 7, 2020
PubMed

Insights

This systematic review examines Vitamin D supplementation

Area of Science:

  • Cardiology
  • Endocrinology
  • Nutritional Science

Background:

  • Coronary artery disease (CAD) is a prevalent cardiovascular condition.
  • Vitamin D may offer benefits to CAD patients by modulating inflammation.
  • This study investigates Vitamin D's impact on inflammatory markers in CAD.

Purpose of the Study:

  • To systematically review the effects of Vitamin D supplementation on inflammatory markers in patients with coronary artery disease.
  • To evaluate Vitamin D's efficacy in managing inflammation associated with CAD.

Main Methods:

  • Systematic literature search of electronic databases and reference lists.
  • Independent screening and data extraction by two investigators.
  • Analysis of primary outcomes (inflammatory biomarkers) and secondary outcomes (lipid profile, blood pressure).

Main Results:

  • The study aims to provide reliable evidence on Vitamin D's efficacy in reducing inflammation in CAD patients.
  • Results will assess the impact of Vitamin D on key inflammatory biomarkers.

Conclusions:

  • The review will determine if Vitamin D supplementation is an effective intervention for reducing inflammation in coronary artery disease patients.
  • Findings will inform clinical practice regarding Vitamin D use in CAD management.
Abstract

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