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Updated: Dec 12, 2025

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
Obsessions and Time of Day: A Self-Monitoring Study in Individuals With Obsessive-Compulsive Disorder
Jacob A Nota1, Brandon E Gibb2, Meredith E Coles2
1Binghamton University Jnota1@binghamton.edu.
Abstract:
Deepening our understanding of the basic mechanisms underlying obsessive-compulsive disorder (OCD) often leads to advances in clinical practice. And, as noted by Kazdin (2008), clinical experiences are an important resource for identifying novel targets for empirical study. One potential target for furthering our understanding of OCD is to investigate clinical reports of within-day symptom fluctuations. Self-monitoring data from 17 adults with OCD were used to test for a diurnal pattern in obsessions. Results from generalized estimating equations revealed that obsessions were most common during midday and that the midday exacerbation was briefer in males. In combination with prior findings of similar diurnal patterns for other anxious symptoms (e.g., panic), these findings suggest that daily social rhythms and/or circadian influences may influence levels of obsessions. Furthermore, treatment may be improved by attending to these heightened symptom periods and integrating this information into therapy (e.g., when developing the exposure hierarchy).
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