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Updated: Dec 12, 2025

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Predictive Immune Modeling of Solid Tumors
Published on: February 25, 2020
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Quest for Ideal Composite Biomarkers for Response to Immunotherapies
Umang Swami1, Roberto H Nussenzveig1, Neeraj Agarwal2
1Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah.
Abstract:
In the CheckMate 275 study, composite biomarkers appear to better predict response to immunotherapy over individual ones. Nevertheless, the path forward needs consensus guidelines for biomarker interpretation. Thereafter, prospective validation with real-time, serial biospecimen collection along with the development of composite biomarker models leads to the goal of personalized therapy.See related article by Galsky et al., p. 5120.

