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Updated: Dec 12, 2025

Visualization of SARS-CoV-2 using Immuno RNA-Fluorescence In Situ Hybridization
Published on: December 23, 2020
Integrative illustration for coronavirus outreach
David S Goodsell1,2, Maria Voigt1,3, Christine Zardecki1,3
1RCSB Protein Data Bank, Rutgers, The State University of New Jersey, Piscataway, New Jersey, United States of America.
Two illustrations detail severe acute respiratory syndrome (SARS) coronaviruses and their life cycles. These widely used educational resources are freely available from the Protein Data Bank (PDB)-101.
Area of Science:
- Virology
- Molecular Biology
- Science Education
Background:
- Severe acute respiratory syndrome (SARS) coronaviruses are significant pathogens.
- Understanding the viral life cycle is crucial for combating SARS.
- Effective science communication tools are needed for education and outreach.
Purpose of the Study:
- To present two detailed illustrations of SARS coronaviruses.
- To integrate current knowledge on the SARS coronavirus life cycle.
- To document the dissemination and educational impact of these resources.
Main Methods:
- Creation of scientific illustrations based on current knowledge.
- Integration of these illustrations into an educational resource.
- Free distribution of the resource via the Protein Data Bank (PDB)-101 portal.
Main Results:
- Two comprehensive illustrations depicting SARS coronaviruses and their life cycles were developed.
- These illustrations have been widely adopted for educational and outreach purposes.
- The resources are accessible through the RCSB PDB's education portal, PDB-101.
Conclusions:
- The developed illustrations serve as valuable tools for understanding SARS coronaviruses.
- Free and accessible educational resources enhance scientific literacy.
- Effective visualization aids in the dissemination of complex scientific information.
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