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Updated: Dec 12, 2025

Characterizing Extracellular Vesicles from Biological Fluids
Published on: February 28, 2025
Extracellular Vesicles in Fungi: Past, Present, and Future Perspectives
Juliana Rizzo1, Marcio L Rodrigues2,3, Guilhem Janbon1
1Unité Biologie des ARN des Pathogènes Fongiques, Département de Mycologie, Institut Pasteur, Paris, France.
Abstract:
Extracellular vesicles (EVs) have garnered much interest in the cell biology and biomedical research fields. Many studies have reported the existence of EVs in all types of living cells, including in fifteen different fungal genera. EVs play diverse biological roles, from the regulation of physiological events and response to specific environmental conditions to the mediation of highly complex interkingdom communications. This review will provide a historical perspective on EVs produced by fungi and an overview of the recent discoveries in the field. We will also review the current knowledge about EV biogenesis and cargo, their role in cell-to-cell interactions, and methods of EV analysis. Finally, we will discuss the perspectives of EVs as vehicles for the delivery of biologically active molecules.
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