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Updated: Dec 12, 2025

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The Sciatic Nerve Cuffing Model of Neuropathic Pain in Mice
Published on: July 16, 2014
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Gabapentin for presumed neuropathic ocular pain
Raman Michael1, Johnathan V Jeffers2, Wyatt Messenger2
1University of Illinois at Chicago College of Medicine, USA.
American Journal of Ophthalmology Case Reports
|August 8, 2020
Summary
This case study highlights chronic neuropathic ocular pain in a patient with no visual complaints. Gabapentin effectively resolved the pain, suggesting it may be an underutilized treatment for ocular discomfort.
Area of Science:
- Ophthalmology
- Neurology
Background:
- Neuropathic ocular pain can occur without apparent visual deficits.
- Laser-assisted in situ keratomileusis (LASIK) complications can predispose patients to ocular pain.
Observation:
- A 37-year-old male with a history of LASIK, corneal ectasia, and glaucoma drainage implant presented with 8 months of left eye pain.
- Comprehensive ophthalmic and imaging evaluations were performed.
Findings:
- Complete resolution of chronic ocular pain was achieved after 3 weeks of gabapentin treatment.
- Gabapentin demonstrated efficacy in managing neuropathic ocular pain.
Implications:
- The pathophysiology of neuropathic ocular pain requires further investigation.
- Gabapentin may be an underutilized therapeutic option for chronic ocular pain.
- Ophthalmologists should consider neuropathic pain in patients with unexplained ocular discomfort.
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