Transient Cardiomyopathy in a Patient With Coronavirus Disease-2019

B K Anupama1, Simant S Thapa1, Ioana Amzuta1

  • 1SUNY Upstate Medical University, Syracuse, NY, USA.

Insights

Severe COVID-19 can cause temporary heart muscle damage (cardiomyopathy) and shock. Treatment with convalescent plasma and inotropic support led to full recovery of heart function in one patient.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Coronavirus disease-19 (COVID-19) has been associated with various cardiovascular complications.
  • Systemic inflammation plays a significant role in the pathophysiology of severe COVID-19.

Observation:

  • A 66-year-old male patient with severe COVID-19 presented with cardiogenic shock.
  • Echocardiography revealed decreased left ventricular ejection fraction and global hypokinesia.
  • The patient exhibited a robust systemic inflammatory response.

Findings:

  • Convalescent plasma therapy and inotropic support were administered.
  • Left ventricular function fully recovered following treatment.
  • Cardiac function recovery correlated with a decrease in inflammatory markers.

Implications:

  • This case demonstrates transient, reversible cardiomyopathy in severe COVID-19.
  • Acute cardiac dysfunction in COVID-19 is associated with profound systemic inflammation.
  • Understanding this association may guide therapeutic strategies for cardiac complications in COVID-19.

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