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Leukocytoclastic Vasculitis as the Presenting Symptom of Crohn's Disease in an Adolescent
Vanessa Ford1, Cassandra Mooney1, Meera Shah1
1Children's Hospital of Atlanta, Atlanta, GA, USA.
Insights
Leukocytoclastic vasculitis (LCV) is a rare condition. This case highlights LCV as an unusual early sign of pediatric Crohn's disease, emphasizing atypical symptom recognition.
Area of Science:
- Vascular Inflammation
- Pediatric Gastroenterology
Background:
- Leukocytoclastic vasculitis (LCV) is a rare inflammatory condition affecting post-capillary venules, with increasing incidence with age.
- LCV as a presenting symptom of inflammatory bowel disease (IBD) is uncommon, particularly in pediatric cases.
Abstract:
Leukocytoclastic vasculitis (LCV) is a rare vascular inflammatory condition that affects post-capillary venules. Its incidence in the pediatric population is unknown. However, its incidence has been shown to increase with age. The causes of LCV can be varied, ranging from drugs to infections to systemic disease. LCV as a presenting symptom of inflammatory bowel disease (IBD) is rare, especially in the pediatric population. A 15-year-old female with a family history of systemic lupus erythematosus was transferred to our hospital with a month-long history of rash, joint swelling and tenderness, periorbital edema, weight loss, and diarrhea. She presented with the objective findings of a biopsy showing LCV and a computed tomography scan read that was concerning for IBD versus infectious colitis. She had a thorough workup, involving both the rheumatology and gastroenterology services, and was ultimately found to have Crohn's disease. This case reveals the importance of recognition of a constellation of symptoms in IBD even when they are not classical in nature at initial presentation.
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