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Updated: Dec 12, 2025
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Optimized Bone Sampling Protocols for the Retrieval of Ancient DNA from Archaeological Remains
Published on: November 30, 2021
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Fostering Responsible Research on Ancient DNA
Jennifer K Wagner1, Chip Colwell2, Katrina G Claw3
1Professional Practice and Social Implications Committee (formerly the Social Issues Committee), American Society of Human Genetics, Bethesda, MD 20814, USA; Responsible Ancient DNA Research Working Group, American Society of Human Genetics, Bethesda, MD 20814, USA; Center for Translational Bioethics and Health Care Policy, Geisinger, Danville, PA 17822, USA.
American Journal of Human Genetics
|August 9, 2020
Summary
Scientists studying ancient DNA must engage communities ethically. This involves consultation, addressing cultural concerns, capacity building, clear data management, and long-term stewardship for responsible research practices.
Area of Science:
- Bioethics
- Paleogenomics
- Archaeology
Background:
- Scientific advancements, particularly in ancient DNA (aDNA) research, necessitate evolving ethical considerations.
- Understanding the social implications of scientific work is a core responsibility for researchers.
- Contemporary practices in ancient human remains research require robust community engagement.
Purpose of the Study:
- To provide practical recommendations for ethical engagement in ancient DNA research.
- To foster collaboration and mutual understanding between researchers and descendant communities.
- To promote responsible stewardship of ancient DNA data and findings.
Main Methods:
- Development of five key recommendations for ethical ancient DNA research practices.
- Emphasis on community consultation and addressing cultural and ethical considerations.
- Guidelines for reporting results, data management, and long-term stewardship.
Main Results:
- Formalized consultation with affected communities is crucial.
- Integration of cultural and ethical considerations into research protocols is essential.
- Community engagement and capacity building strengthen research integrity and social responsibility.
Conclusions:
- Ethical ancient DNA research requires proactive engagement with communities.
- Researchers must plan for result dissemination, data management, and long-term stewardship.
- Shared responsibility among research team members is vital for upholding ethical standards.
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