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Updated: Jun 22, 2026

Bacterial Artificial Chromosomes: A Functional Genomics Tool for the Study of Positive-strand RNA Viruses
Published on: December 29, 2015
A Comprehensive, Flexible Collection of SARS-CoV-2 Coding Regions
Dae-Kyum Kim1,2,3, Jennifer J Knapp1,2,3, Da Kuang1,2,3
1Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Abstract:
The world is facing a global pandemic of COVID-19 caused by the SARS-CoV-2 coronavirus. Here we describe a collection of codon-optimized coding sequences for SARS-CoV-2 cloned into Gateway-compatible entry vectors, which enable rapid transfer into a variety of expression and tagging vectors. The collection is freely available. We hope that widespread availability of this SARS-CoV-2 resource will enable many subsequent molecular studies to better understand the viral life cycle and how to block it.
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