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Related Concept Videos

Respiratory Volumes01:15

Respiratory Volumes

2.6K
Respiratory volumes are crucial metrics, meticulously measured to quantify the air exchanged in and out of the lungs during various phases of the breathing cycle. These precise measurements are vital for assessing lung function, diagnosing respiratory conditions, and monitoring overall respiratory health. Each parameter provides specific insights into the mechanics of breathing and the functional capacity of the lungs.
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
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Lung Capacity01:47

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The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
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Respiratory Volumes and Capacities01:22

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The respiratory system is responsible for the intake of oxygen and the expulsion of carbon dioxide from the body. Respiratory volumes describe the volume of air in the lungs at different phases of the respiratory cycle. Tidal volume is the air breathed in and out during normal, quiet breathing. Inspiratory reserve volume is the air that can be forcefully inspired beyond the tidal volume. In contrast, expiratory reserve volume refers to the air that can be expelled from the lungs after a normal...
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Pulmonary Ventilation: Inhalation01:24

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Pulmonary ventilation is a vital process that ensures the exchange of oxygen and carbon dioxide in the lungs. It refers to the movement of air into and out of the lungs, enabling the body to obtain oxygen and remove waste carbon dioxide. In this article, we will explore the intricacies of pulmonary ventilation, including its underlying principles, mechanisms, and the interplay of pressures within the respiratory system.
Boyle's law becomes particularly pertinent when examining respiratory...
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Respiratory Volumes and Capacities I01:26

Respiratory Volumes and Capacities I

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Assessing the respiratory rate and rhythm for a complete minute is crucial for evaluating the breathing pattern. Even a minor increase in the patient's average respiratory rate, by as little as three to five breaths per minute, is an early and vital indicator of respiratory distress. Patients with a respiratory rate exceeding twenty-four breaths per minute require close monitoring to determine the physiological alterations. This careful observation is essential for prompt recognition and...
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Respiratory Capacities01:24

Respiratory Capacities

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Respiratory capacities are crucial indicators of lung function, representing the maximum amount of air an individual's respiratory system can handle during various breathing phases.
One key metric is the Inspiratory Capacity (IC), which represents the maximum amount of air that can be inhaled with full effort. IC is calculated by summing the tidal volume and inspiratory reserve volume, typically ranging from 2.4 to 3.6 liters.
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Related Experiment Video

Updated: Dec 12, 2025

Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models
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The Difference Between Set and Delivered Tidal Volume: A Lung Simulation Study.

Yoshikazu Yamaguchi1,2,3, Tetsuya Miyashita1, Yuko Matsuda1

  • 1Department of Anesthesiology and Critical Care, Yokohama City University, Kanagawa, Japan.

Medical Devices (Auckland, N.Z.)
|August 9, 2020
PubMed
Summary

Accurate tidal volume delivery in neonates is crucial for preventing lung injury. The Evita Infinity ICU ventilator demonstrated superior accuracy compared to other tested ventilators, even with simulated lung injury.

Keywords:
flow sensorlung protective ventilationmechanical ventilationpediatric anesthesiatidal volumevolutrauma

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Area of Science:

  • Mechanical Ventilation
  • Neonatal Respiratory Care
  • Pulmonary Mechanics

Background:

  • Precise tidal volume (VT) control is essential for limiting ventilator-induced lung injury (VILI) in neonates.
  • Ensuring adequate ventilation requires accurate delivery of set tidal volumes (sVT).
  • Discrepancies between measured (mVT) and actual (aVT) tidal volumes can compromise patient safety.

Purpose of the Study:

  • To compare the accuracy of tidal volume delivery between different mechanical ventilators in a neonatal lung model.
  • To evaluate the impact of simulated lung injury on tidal volume accuracy.
  • To determine which ventilator provides the most reliable tidal volume delivery in simulated neonatal respiratory scenarios.

Main Methods:

  • Utilized the ASL5000 lung simulator to mimic neonatal respiratory parameters (resistance and compliance).
  • Tested three ventilators: Drager Fabius GS (anesthesia), Servo-i Universal (ICU), and Evita Infinity V500 (ICU).
  • Evaluated ventilators in volume-controlled ventilation (VCV) and dual-controlled ventilation (DCV) modes with a set tidal volume of 30 mL and respiratory rate of 25 breaths/minute.

Main Results:

  • The Drager Fabius GS exhibited the highest discrepancies between sVT, mVT, and aVT, which worsened with simulated lung injury.
  • The Servo-i showed greater differences in VT delivery compared to the Evita Infinity, particularly in DCV mode and with simulated lung injury.
  • The Evita Infinity ICU ventilator consistently achieved accurate tidal volumes across all tested conditions.

Conclusions:

  • The Evita Infinity ICU ventilator is the only device tested that accurately delivers tidal volumes in simulated neonatal ventilation.
  • Ventilator accuracy is independent of the ventilation mode (VCV or DCV) when using the Evita Infinity.
  • The Evita Infinity maintains accurate tidal volume delivery even under conditions of simulated lung injury.