Unilateral morning glory disc anomaly in a patient with prenatal Zika virus exposure
Sofía M Muns1, Mónica P González1, Victor M Villegas1,2,3
1Department of Ophthalmology, University of Puerto Rico, Medical Sciences Campus, San Juan, PR 00936-5067 USA.
Background:
To report a case of morning glory disc anomaly (MGDA) in a pediatric patient with prenatal Zika virus (ZIKV) exposure.
Case Presentation:
A 3-year-old male with prenatal exposure to ZIKV, confirmed by real-time polymerase chain reaction testing during the second trimester of pregnancy, was evaluated due to visual loss. Physical examination was remarkable for unilateral MGDA. Neuroimaging showed a base of skull encephalocele through the floor of the sella and callosal dysgenesis.
Conclusions:
This is the first report to suggest an association between prenatal ZIKV exposure and MGDA. Prenatal ZIKV exposure may be associated to a wider pathologic spectrum than previously reported.
