Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Upper Extremity Surgical Outcomes in Transgender Trauma Patients.

Cureus·2026

Same author

Complex Open Fractures of the Lower Extremity: What is the Optimal Time from Bone Fixation to Flap Coverage?

Journal of reconstructive microsurgery·2025

Same author

First-in-human implementation of a bidirectional somatosensory neuroprosthetic system with wireless communication.

Journal of neuroengineering and rehabilitation·2025

Same author

Optimizing Postoperative Anticoagulation Regimen to Improve Lower Extremity Free Flap Outcomes.

Journal of reconstructive microsurgery·2025

Same author

Is more better? Evaluating the impact of early surgical debridement on Morel-Lavallee lesions.

American journal of surgery·2025

Same author

First Extensor Compartment Entrapment After Distal Radius Fracture: Case Report.

Cureus·2024

Search research articles

Related Experiment Video

Updated: Dec 12, 2025

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

Published on: March 8, 2024

Targeted Muscle Reinnervation for Partial Hand Amputation.

Kyle J Chepla¹, Yuewei Wu-Fienberg¹

¹Division of Plastic Surgery, MetroHealth Medical Center, Cleveland, Ohio.

Plastic and Reconstructive Surgery. Global Open

|August 9, 2020

Summary

This summary is machine-generated.

Targeted muscle reinnervation (TMR) shows promise for treating neuroma pain after upper limb amputation. This cadaver study suggests TMR is feasible for partial hand and finger amputations, potentially reducing pain.

More Related Videos

Therapy Interventions for Upper Limb Amputees Undergoing Selective Nerve Transfers

Therapy Interventions for Upper Limb Amputees Undergoing Selective Nerve Transfers

Published on: October 29, 2021

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management

Published on: March 15, 2024

Related Experiment Videos

Last Updated: Dec 12, 2025

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

Published on: March 8, 2024

Therapy Interventions for Upper Limb Amputees Undergoing Selective Nerve Transfers

Therapy Interventions for Upper Limb Amputees Undergoing Selective Nerve Transfers

Published on: October 29, 2021

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management

Published on: March 15, 2024

Area of Science:

Neurosurgery
Regenerative Medicine
Pain Management

Background:

Targeted muscle reinnervation (TMR) is an established treatment for symptomatic neuromas in upper limb amputations.
Previous studies on TMR for shoulder disarticulation, transhumeral, and transradial amputations show promising outcomes in reducing phantom limb and residual limb pain.

Purpose of the Study:

To investigate the feasibility of applying TMR to treat symptomatic neuromas after partial hand and finger amputations.
To assess the anatomical viability of nerve transfers in the hand for TMR.

Main Methods:

Cadaver dissection of motor branches from the median and ulnar nerves in the forearm and hand.
Simulated nerve transfers involving digital nerves, common digital nerves, and the recurrent motor branch of the ulnar nerve.

Main Results:

Identification of all relevant nerve branches under loupe magnification.
Successful simulation of digital nerve transfers to lumbrical motor branches and common digital nerves to motor branches.
Demonstrated potential for transferring the common sensory portion of the ulnar nerve to a hypothenar motor branch.

Conclusions:

The anatomical proximity of sensory nerves to motor branches supports TMR feasibility in partial hand/finger amputations.
Abundant redundant motor nerve targets exist for TMR in the hand.
Further clinical studies are needed to refine indications and evaluate outcomes for TMR in partial hand amputations.