Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The Common Fund Data Ecosystem (CFDE).

bioRxiv : the preprint server for biology·2026

Same author

Learning Explainable Imaging-Genetics Associations Related to a Neurological Disorder.

Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention·2026

Same author

Assembling unmapped reads reveals hidden variation in South Asian genomes.

Nature communications·2026

Same author

Training biologists in Unix command-line skills: From curriculum to interactive online tutorials.

PLoS computational biology·2026

Same author

Perseus: Lineage-Aware Refinement of Kraken2 Taxonomic Classification for Long Read Metagenomes.

bioRxiv : the preprint server for biology·2026

Same author

A neofunctionalized flowering antagonist created an evolutionary contingency that channeled Solanaceae adaptation.

bioRxiv : the preprint server for biology·2026

Same journal

3DICE: Interpretable 3D Cross-Modal Learning for Drug-Target Interaction Prediction and Large-Scale Drug Discovery.

Bioinformatics (Oxford, England)·2026

Same journal

KASSPer: Kinase Active Site Structure Prediction using Protein and Ligand Language Models and Its Application to Virtual Screening.

Bioinformatics (Oxford, England)·2026

Same journal

IDR searcher: a search engine solution for public image resources.

Bioinformatics (Oxford, England)·2026

Same journal

KCFtools: Rapid alignment-free method for introgression screening and GWAS using k-mer profiles.

Bioinformatics (Oxford, England)·2026

Same journal

Meta2DB: Curated shotgun metagenomic feature sets and metadata for health state prediction.

Bioinformatics (Oxford, England)·2026

Same journal

conMItion: an R package adjusting confounding factors for associations in multi-omics.

Bioinformatics (Oxford, England)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Dec 11, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

Ribbon: intuitive visualization for complex genomic variation.

Maria Nattestad¹, Robert Aboukhalil², Chen-Shan Chin³

¹Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

Bioinformatics (Oxford, England)

|August 9, 2020

Summary

This summary is machine-generated.

Ribbon is a new visualization tool for understanding structural variants and their supporting long-read evidence. It aids in curating complex variant calls and genome comparisons with an intuitive interface.

More Related Videos

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Published on: December 7, 2021

Visualizing Genetic Variants, Short Targets, and Point Mutations in the Morphological Tissue Context with an RNA In Situ Hybridization Assay

Visualizing Genetic Variants, Short Targets, and Point Mutations in the Morphological Tissue Context with an RNA In Situ Hybridization Assay

Published on: August 14, 2018

Related Experiment Videos

Last Updated: Dec 11, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Published on: December 7, 2021

Visualizing Genetic Variants, Short Targets, and Point Mutations in the Morphological Tissue Context with an RNA In Situ Hybridization Assay

Visualizing Genetic Variants, Short Targets, and Point Mutations in the Morphological Tissue Context with an RNA In Situ Hybridization Assay

Published on: August 14, 2018

Area of Science:

Genomics
Bioinformatics
Computational Biology

Background:

Structural variants (SVs) are crucial in genomic diversity and disease.
Accurate curation of SVs requires robust visualization of supporting evidence.
Existing tools may not provide an intuitive view of SVs within reference and read contexts.

Purpose of the Study:

To introduce Ribbon, a novel alignment visualization tool.
To facilitate the understanding of structural variants and their supporting long-read evidence.
To assist in the curation of complex structural variant calls.

Main Methods:

Ribbon visualizes alignment positions in reference and read contexts.
The tool provides an intuitive interface for examining structural variants.
It is applicable to both long-read evidence and genome-to-genome comparisons.

Main Results:

Ribbon offers an intuitive understanding of structural variants.
It effectively displays read evidence supporting structural variants.
The tool aids in curating complex structural variant calls.

Conclusions:

Ribbon enhances the understanding of structural variants and their supporting evidence.
The tool is valuable for curating complex variant calls.
Ribbon's visualization method is effective for genome-to-genome comparisons.