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Updated: Dec 12, 2025

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Assessment of Viability of Human Fat Injection into Nude Mice with Micro-Computed Tomography
Published on: January 7, 2015
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Long-Term Survival of Fat Transplants: Controlled Demonstrations
1, 5 East 82 Street, New York, NY, 10028, USA.
Aesthetic Plastic Surgery
|August 9, 2020
Summary
Autologous fatty tissue transplantation offers a potentially permanent solution for correcting creases, with studies showing no recurrence over six years. This technique demonstrates lasting results in facial rejuvenation.
Area of Science:
- Plastic Surgery
- Dermatology
- Regenerative Medicine
Background:
- Facial creases and wrinkles are common aesthetic concerns.
- Fatty tissue transplantation is a method for soft tissue augmentation.
- Understanding the long-term viability of transplanted fat is crucial for clinical application.
Purpose of the Study:
- To document the amount and rate of re-absorption of transplanted autologous fatty tissue.
- To evaluate the longevity and efficacy of fatty tissue transplantation for crease correction.
- To assess the permanence of results achieved with the author's specific transplantation technique.
Main Methods:
- Controlled studies initiated in 1987.
- Infiltration of a selected crease with autologous fatty tissue.
- Comparison with a nearby untreated crease as a control.
- Serial photographic documentation over six years (yearly intervals).
Main Results:
- Absence of crease recurrence in the infiltrated area over the six-year follow-up.
- Control creases remained unchanged or deepened, indicating the effectiveness of the fat graft.
- Photographic evidence supported the sustained correction in all views and lighting conditions.
Conclusions:
- Fatty tissue transplantation demonstrates a potential for permanent correction of facial creases.
- The author's technique shows lasting results, supported by extensive clinical practice.
- This method offers a durable option for facial rejuvenation and wrinkle correction.

