Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

iPS Cell Differentiation01:22

iPS Cell Differentiation

3.0K
The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
3.0K
Induced Pluripotent Stem Cells01:06

Induced Pluripotent Stem Cells

5.1K
Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic...
5.1K
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

26.7K
Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
26.7K
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.5K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.5K
Adult Stem Cells01:33

Adult Stem Cells

32.8K
Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
32.8K
Stem Cell Culture01:17

Stem Cell Culture

5.9K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
5.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Encouraging effect of autologous bone marrow aspirate concentrate in rehabilitation of children with cerebral palsy.

European review for medical and pharmacological sciences·2022
Same author

Serum cytokine profile of laryngeal squamous cell carcinoma patients.

The Journal of laryngology and otology·2017
Same author

Middle turbinate chondro-osseous respiratory epithelial adenomatoid hamartoma.

B-ENT·2015
Same author

Inhibition of mitochondrial Na+-dependent Ca²+ efflux by 17β-estradiol in the rat hippocampus.

Neuroscience·2011
Same author

Psychological well-being in advanced NSCLC patients in Serbia: impact of sociodemographic and clinical factors.

Neoplasma·2009
Same author

Detection of ZAP-70 in patients with chronic lymphocytic leukemia.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology·2009

Related Experiment Video

Updated: Dec 12, 2025

Systemic Injection of Neural Stem/Progenitor Cells in Mice with Chronic EAE
09:24

Systemic Injection of Neural Stem/Progenitor Cells in Mice with Chronic EAE

Published on: April 15, 2014

18.0K

Autism treatment with stem cells: a case report.

D M Maric1, V Papic, M Radomir

  • 1Clinic Orto MD-Global Care Surgery Hospital, Novi Sad, Serbia. dusica.maric@mf.uns.ac.rs.

European Review for Medical and Pharmacological Sciences
|August 9, 2020
PubMed
Summary

This study shows that bone marrow mononuclear cell (BMAC) transplantation can improve communication in children with autism spectrum disorder (ASD). The treatment offers a potential new avenue for managing ASD symptoms and enhancing quality of life.

More Related Videos

Isolation, Enrichment, and Maintenance of Medulloblastoma Stem Cells
06:32

Isolation, Enrichment, and Maintenance of Medulloblastoma Stem Cells

Published on: September 1, 2010

16.6K
Derivation of Human Embryonic Stem Cells by Immunosurgery
11:56

Derivation of Human Embryonic Stem Cells by Immunosurgery

Published on: December 13, 2007

34.5K

Related Experiment Videos

Last Updated: Dec 12, 2025

Systemic Injection of Neural Stem/Progenitor Cells in Mice with Chronic EAE
09:24

Systemic Injection of Neural Stem/Progenitor Cells in Mice with Chronic EAE

Published on: April 15, 2014

18.0K
Isolation, Enrichment, and Maintenance of Medulloblastoma Stem Cells
06:32

Isolation, Enrichment, and Maintenance of Medulloblastoma Stem Cells

Published on: September 1, 2010

16.6K
Derivation of Human Embryonic Stem Cells by Immunosurgery
11:56

Derivation of Human Embryonic Stem Cells by Immunosurgery

Published on: December 13, 2007

34.5K

Area of Science:

  • Neuroscience
  • Regenerative Medicine

Background:

  • Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition requiring early intervention for improved outcomes.
  • Classifying children with ASD at a young age is crucial for accessing effective evidence-based therapies.

Observation:

  • A case study involved a child with autism undergoing intrathecal autologous bone marrow mononuclear cells transplantation and neurorehabilitation.
  • Following the procedure, the child exhibited speech improvement, reflected in a GARS-2 assessment score of 91 (27% autism index).

Findings:

  • The study provides evidence supporting the safety and effectiveness of bone marrow mononuclear cell (BMAC) transplantation for managing autism.
  • Significant improvement in communication skills was observed post-treatment.

Implications:

  • BMAC transplantation presents a promising therapeutic option for children with ASD.
  • This approach may enhance the quality of life for individuals with autism spectrum disorder.