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Palmar-plantar erythrodysesthesia associated with high-dose methotrexate: Case report

Priyanka Chauhan1, Anshul Gupta1, Sujeet Kumar1

  • 1Department of Hematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.

Cancer Reports (Hoboken, N.J.)
|August 9, 2020
PubMed
Abstract

Keywords:
methotrexatepalmar-plantar erythrodysesthesia

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Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
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