Current Status of Etiology, Epidemiology, Clinical Manifestations and Imagings for COVID-19

Meng Di Jiang1, Zi Yue Zu1, U Joseph Schoepf2

  • 1Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.

Insights

Chest CT scans are crucial for identifying Coronavirus disease 2019 (COVID-19), assessing its severity, and monitoring its progression. This review offers radiologists updated knowledge on COVID-19 imaging.

Area of Science:

  • Radiology
  • Infectious Diseases
  • Medical Imaging

Background:

  • Coronavirus disease 2019 (COVID-19) is a global pandemic originating in Wuhan, China.
  • Chest CT imaging has become essential for COVID-19 diagnosis and management.
  • Existing knowledge on COVID-19 etiology, epidemiology, and pathology is rapidly expanding.

Purpose of the Study:

  • To provide radiologists with an updated framework for understanding COVID-19.
  • To consolidate essential knowledge regarding the role of imaging in COVID-19.
  • To highlight the importance of recognizing extrapulmonary manifestations and complications.

Main Methods:

  • Review of published literature on COVID-19.
  • Analysis of the role of chest CT in disease identification and monitoring.
  • Synthesis of current understanding of COVID-19's imaging spectrum.

Main Results:

  • Chest CT is vital for early identification, severity assessment, and disease course monitoring of COVID-19.
  • Published data has significantly advanced understanding of COVID-19's characteristics.
  • The imaging spectrum of COVID-19 is evolving, necessitating attention to extrapulmonary findings.

Conclusions:

  • Radiologists require updated knowledge to effectively manage COVID-19 patients.
  • Chest CT plays a pivotal role throughout the patient care pathway for COVID-19.
  • Continued research is needed to fully define the imaging features and complications of COVID-19.

Related Concept Videos

COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
1.6K
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
276
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
157
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
297
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
2.2K
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
114