Related Experiment Video

Updated: Dec 12, 2025

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
11:50

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

Published on: July 9, 2010

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Longitudinal Echocardiographic Assessment of Coronary Arteries and Left Ventricular Function following Multisystem

Simone Jhaveri1, Neha Ahluwalia1, Shubhi Kaushik2

  • 1Department of Pediatric Cardiology, Icahn School of Medicine at Mount Sinai, New York.

The Journal of Pediatrics
|August 10, 2020
PubMed

Insights

Multisystem inflammatory syndrome in children (MIS-C) can cause heart problems like myocardial dysfunction and coronary artery dilation. This study tracked 15 children with MIS-C to understand short-term cardiac outcomes.

Area of Science:

  • Pediatric Cardiology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Severe acute respiratory syndrome coronavirus disease-2 (SARS-CoV-2) infection can lead to multisystem inflammatory syndrome in children (MIS-C).
  • Cardiac involvement, including myocardial dysfunction and coronary artery dilation, is a recognized complication of MIS-C.

Observation:

  • This single-center study longitudinally assessed 15 pediatric patients diagnosed with MIS-C.
  • Echocardiography was utilized to evaluate cardiac function and coronary artery dimensions.

Findings:

  • The study reports on the short-term cardiac outcomes in children experiencing MIS-C.
  • Observed outcomes included persistent myocardial dysfunction and coronary artery dilation in the studied cohort.

Implications:

  • Understanding the short-term cardiac sequelae of MIS-C is crucial for timely intervention and management.
  • Further research into the long-term cardiac effects of MIS-C is warranted.
  • This data can inform clinical guidelines for managing pediatric patients with MIS-C and associated cardiac complications.

Keywords:
COVID-19coronary aneurysmcoronary dilationpediatricssystolic dysfunction

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