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Updated: Dec 12, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
Cluster infections play important roles in the rapid evolution of COVID-19 transmission: A systematic review
Tao Liu1, Dexin Gong1, Jianpeng Xiao1
1Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
Objectives:
To summarise the major types of SARS-CoV-2 cluster infections worldwide through a comprehensive systematic review.
Methods:
All studies published between 01 January-15 June 2020 on COVID-19 cluster infections in English electronic databases were searched, including PubMed, Embase, Web of Knowledge, and Scopus. All included studies were independently screened and evaluated by two authors, and information from each study was extracted using a standard form.
Results:
Sixty-five studies were included, which involved 108 cluster infections from 13 countries, areas or territories. Seventy-two (66.7%) of the cluster infections were reported in China. The major types of cluster infections were families, community transmission, nosocomial infection, gatherings, transportation, shopping malls, conferences, tourists, religious organisations, workers, prisons, offices, and nursing homes.
Conclusions:
The SARS-CoV-2 can be transmitted in various circumstances, and cluster infections play an important role in the rapid evolution of COVID-19 transmission. Prevention and control measures such as social distancing must be strictly implemented to contain these cluster infections.
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