Related Experiment Video

Updated: Dec 12, 2025

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
05:41

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Published on: December 16, 2022

4.1K

Gender-related Disparities of Percutaneous Coronary Interventions in ST-elevation Myocardial Infarction: A

Elsa Sleiman1, Jeff Hosry1, Lisa Caruana2

  • 1From the Department of Internal Medicine, Staten Island University Hospital, NY.

Critical Pathways in Cardiology
|August 10, 2020
PubMed

Insights

This study found no significant gender differences in door-to-balloon times for ST-elevation myocardial infarction patients. Emergency medical services appear to mitigate disparities in percutaneous coronary intervention treatment times.

Area of Science:

  • Cardiology
  • Emergency Medicine
  • Health Disparities Research

Background:

  • Door-to-balloon (DTB) time is critical for ST-elevation myocardial infarction (STEMI) treatment outcomes.
  • Recent data suggested widening gender disparities in DTB times, contradicting previous improvements.

Purpose of the Study:

  • To investigate potential gender-based circadian disparities in percutaneous coronary intervention (PCI) for STEMI.
  • To compare DTB, symptom-to-balloon (STB) times, and mortality between male and female STEMI patients.

Main Methods:

  • Retrospective analysis of 514 STEMI patients (117 female, 397 male) undergoing primary PCI.
  • Comparison of DTB, STB times, and 1-month mortality outcomes stratified by gender.
  • Assessment of baseline characteristics and cardiovascular risk factors.

Main Results:

  • No significant differences were observed in median DTB times (males: 63 min; females: 61 min).
  • Median STB times were also comparable between genders (males: 155 min; females: 165 min).
  • One-month mortality rates were similar: 3% for males and 0.9% for females (P=0.164).

Conclusions:

  • This tertiary care center's data shows no gender disparity in DTB or STB times for STEMI.
  • The findings suggest that standardized emergency medical service transport may effectively eliminate gender-based treatment delays.

More Related Videos

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

2.0K
Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation06:04

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

Published on: August 8, 2025

427

Related Concept Videos

Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
513
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
725
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
276
Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
417
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
122
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
160