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Disentangling fatigue from anhedonia: a scoping review
Ruel R Billones1, Saloni Kumar1, Leorey N Saligan2
1National Institute of Nursing Research, National Institutes of Health, Bethesda, MD, USA.
Translational Psychiatry
|August 10, 2020
Summary
Fatigue and anhedonia are common in chronic illnesses. While often distinct, some research suggests they may be indistinguishable due to shared nomenclature and biology, impacting patient quality of life.
Area of Science:
- Clinical Psychology
- Psychiatry
- Medical Research
Background:
- Fatigue and anhedonia are prevalent, co-occurring symptoms in chronic illnesses.
- These symptoms significantly impair patients' health-related quality of life.
- Differentiating fatigue and anhedonia is crucial for accurate diagnosis and effective treatment.
Purpose of the Study:
- To conduct a scoping review to understand the similarities and differences between fatigue and anhedonia.
- To analyze how existing literature treats these two constructs.
Main Methods:
- A comprehensive literature search was performed using PubMed with "fatigue" and "anhedonia" as Medical Subject Headings.
- An initial search yielded 5254 articles, with a full-text review of 21 final articles.
- Articles were analyzed to determine if they treated fatigue and anhedonia as distinct or indistinguishable constructs.
Main Results:
- Approximately 60% of reviewed articles consider fatigue and anhedonia as distinct constructs.
- A significant portion of the literature found these constructs to be indistinguishable.
- Nomenclature and biological factors emerged as key themes supporting the indistinguishability of fatigue and anhedonia.
Conclusions:
- Understanding the relationship between fatigue and anhedonia is clinically relevant for managing chronic illness symptoms.
- The review highlights the need for clearer definitions and potentially integrated treatment approaches.
- Further research into the shared biological and linguistic underpinnings of fatigue and anhedonia is warranted.
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