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Updated: Dec 12, 2025

Heterogeneous Removal of Water-Soluble Ruthenium Olefin Metathesis Catalyst from Aqueous Media Via Host-Guest Interaction
Published on: August 23, 2018
Recyclable Ruthenium Catalyst for Distal meta-C-H Activation
Isaac Choi1, Valentin Müller1, Yanhui Wang2
1Institut für Organische und Biomolekulare Chemie and, Wöhler Research Institute for Sustainable Chemistry (WISCh), Georg-August-Universität, Tammanstraße 2, 37077, Göttingen, Germany.
Abstract:
We disclose the unprecedented hybrid-ruthenium catalysis for distal meta-C-H activation. The hybrid-ruthenium catalyst was recyclable, as was proven by various heterogeneity tests, and fully characterized with various microscopic and spectroscopic techniques, highlighting the physical and chemical stability. Thereby, the hybrid-ruthenium catalysis proved broadly applicable for meta-C-H alkylations of among others purine-based nucleosides and natural product conjugates. Additionally, its versatility was further reflected by meta-C-H activations through visible-light irradiation, as well as para-selective C-H activations.
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