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Viral enteritis.

J R Hamilton1

  • 1Department of Pediatrics, McGill University, Montreal, Quebec, Canada.

Pediatric Clinics of North America
|February 1, 1988
PubMed
Summary
This summary is machine-generated.

Rotavirus is the leading cause of severe diarrhea in children globally. While vaccines are unavailable, improved hygiene and breastfeeding are key preventive measures against this major enteric pathogen.

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Area of Science:

  • * Virology
  • * Pediatric Gastroenterology
  • * Infectious Diseases

Background:

  • * Rotavirus is the primary global cause of acute gastroenteritis in infants and young children.
  • * Other viral enteric pathogens exist, but rotavirus has the most significant worldwide impact.
  • * Preventive strategies, including hygiene and breastfeeding, are crucial for vulnerable infants.

Purpose of the Study:

  • * To review current understanding of rotavirus pathogenesis and management.
  • * To highlight the importance of preventive measures against rotavirus infection.
  • * To identify remaining challenges in enteric viral pathogen research.

Main Methods:

  • * Review of clinical studies and animal models on rotavirus pathogenesis.

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  • * Analysis of established and suspected enteric viral pathogens.
  • * Evaluation of current therapeutic and preventive approaches.

    • Main Results:

    • * Significant advancements in understanding rotavirus diarrhea pathogenesis over the past decade.
    • * Evidence supports rational oral rehydration therapy and early feeding for management.
    • * Improved hygiene in pediatric settings and breastfeeding reduce illness severity.

    Conclusions:

    • * Rotavirus remains a critical global public health concern for young children.
    • * Preventive measures like enhanced hygiene and breastfeeding are vital.
    • * Further research is needed to identify all enteric viral pathogens and develop effective therapies.