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Dyslipidemia is associated with severe coronavirus disease 2019 (COVID-19) infection

Timotius Ivan Hariyanto1, Andree Kurniawan2

  • 1Faculty of Medicine, Pelita Harapan University, Boulevard Jendral Sudirman Street, Karawaci, Tangerang, 15811, Indonesia.

Diabetes & Metabolic Syndrome
|August 11, 2020
PubMed

Insights

Dyslipidemia, a condition affecting blood lipid levels, is linked to increased severity of coronavirus disease 2019 (COVID-19). Individuals with dyslipidemia require close monitoring to mitigate risks associated with severe COVID-19 outcomes.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • The ongoing increase in coronavirus disease 2019 (COVID-19) cases and fatalities necessitates identifying risk factors for severe outcomes.
  • Dyslipidemia, a known risk factor for cardiovascular disease, is investigated for its potential role in COVID-19 severity.

Purpose of the Study:

  • To analyze the association between dyslipidemia and the severity of COVID-19 infection.

Main Methods:

  • A systematic literature search was conducted on the PubMed database up to July 9th, 2020.
  • Articles on COVID-19 and dyslipidemia were retrieved and analyzed using Review Manager 5.4 software.

Main Results:

  • Seven studies comprising 6922 patients were included in the meta-analysis.
  • Dyslipidemia was found to be associated with severe COVID-19 infections, with a risk ratio of 1.39 (95% CI 1.03-1.87).

Conclusions:

  • Dyslipidemia is a significant risk factor for severe outcomes in COVID-19 infections.
  • Close monitoring of patients with dyslipidemia is recommended to minimize COVID-19-related risks.
Abstract

Keywords:
COVID-19Coronavirus disease 2019DyslipidemiaMetabolic diseaseMetabolic syndrome

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