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A Giant Squamous Cell Carcinoma Arising in a Patient with Hidradenitis Suppurativa
Ezgi Özkur1, İlknur Kivanç Altunay, Mustafa Fevzi Celayir
1In the Department of Dermatology, University of Health Sciences, Şişli Etfal Training and Research Hospital, Istanbul, Turkey, Ezgi Özkur, MD, is a dermatologist; İlknur Kivanç Altunay, Prof Dr, is a dermatologist; Mustafa Fevzi Celayir, MD, is a general surgeon; Asli Aksu Çerman, Assoc Prof Dr, is a dermatologist; and Ramazan Uçak, MD, is a pathologist. The authors have disclosed no financial relationships related to this article. Submitted September 3, 2019; accepted in revised form October 31, 2019.
Abstract:
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease of follicular pilosebaceous units. Chronic, active, and poorly controlled disease may lead to squamous cell carcinoma (SCC). The diagnosis and treatment of SCC in HS is particularly challenging because SCC lesions may be easily mistaken for HS lesions. Current medical literature recommends aggressive surgical excision with at least 2-cm margins. In this article, the authors describe a giant perianal SCC arising in a patient with HS who was treated with surgical resection and radiotherapy.
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