Extramedullary plasmacytoma of hypopharynx treated using transoral laser microsurgery and adjuvant radiotherapy

Extramedullary plasmacytoma (EMP) of the hypopharynx is exceedingly rare. There were only two cases reported before. A 77-year-old man was presented with a 6-month history of foreign body sensation in the throat. Nasopharyngoscopy revealed an exophytic tumor over the right pyriform sinus. Transoral laser microsurgery was performed 3 weeks later. The pathology report showed aggregates of plasma cells with eccentric nuclei and perinuclear halos (compatible with plasmacytoma). Postoperative radiotherapy was performed, and there was no evidence of tumor recurrence after an 18-month follow-up. This is the first report of transoral laser microsurgery with postoperative radiotherapy in plasmacytoma of hypopharynx, and it resulted in optimal tumor control and minimal morbidity.