Related Experiment Video
Updated: Dec 12, 2025

Author Spotlight: Enhancing Rheumatoid Arthritis Research Through HR-pQCT Imaging Analysis
Published on: October 6, 2023
Hemorrhagic Synovitis of the First Metatarsophalangeal Joint: A Case Report
William P Ensminger1, Elizabeth Friedman2, Kimberly J Templeton1
1Department of Orthopedic Surgery, University of Kansas Medical Center Kansas City, Kansas.
Case:
A 69-year-old woman presented with a painful mass at her first metatarsophalangeal joint. Further evaluation was concerning for a neoplastic process, leading to surgical intervention. Pathological examination demonstrated hemosiderotic synovitis, and hematologic evaluation led to a new diagnosis of von Willebrand disease.
Conclusion:
Hemorrhagic synovitis, involving mostly larger joints, has been well described. However, a literature search demonstrates no cases of this in the foot or toes. Presentation of hemarthroses and underlying coagulopathies can be subtle and must be considered in patients presenting with soft-tissue masses or pseudotumors, despite having no previous diagnosis.
Related Concept Videos
Endocarditis II: Clinical Features of Infective Endocarditis
Development of the Limb Synovial Joints
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
