Related Experiment Video
Updated: Dec 12, 2025

05:19
Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery
Published on: December 1, 2023
1.5K
Lens-Induced Uveitis Triggered by Intravitreal Injection 40 Years after Primary Congenital Cataract Surgery with
Sophia El Hamichi1,2, Rafael J Aguilar1, Veronica Kon Graversen1
1Miami Ocular Oncology and Retina, Miami, Florida, USA.
Case Reports in Ophthalmology
|August 11, 2020
Summary
A patient with diabetes mellitus type 1 experienced pseudo-endophthalmitis after intravitreal injections for macular edema. Surgical intervention led to significant visual recovery and improved eye function.
Area of Science:
- Ophthalmology
- Retinal diseases
- Surgical complications
Background:
- Congenital cataract surgery can lead to long-term complications such as aphakia and secondary glaucoma.
- Diabetes mellitus type 1 increases the risk of ocular complications, including diabetic macular edema.
Observation:
- A 42-year-old male with a history of bilateral congenital cataract surgery presented with complications including aphakia, secondary glaucoma, and diabetic macular edema.
- The patient developed acute pseudo-endophthalmitis in the left eye after multiple intravitreal injections for macular edema, characterized by decreased vision and anterior inflammation.
Findings:
- The pseudo-endophthalmitis was localized around the anterior residual lens capsule.
- Surgical removal of the residual capsule and primary vitrectomy repair resulted in significant visual improvement and functional recovery.
Implications:
- This case highlights the potential for severe intraocular inflammation following intravitreal injections in patients with complex ocular histories.
- Prompt surgical management can effectively treat pseudo-endophthalmitis and restore visual function in challenging cases.
Related Concept Videos
Glaucoma: Overview
1.1K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.1K
Angle Closure Glaucoma: Treatment
1000
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1000
Open Angle Glaucoma: Treatment
865
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
865
Photoreceptors and Visual Pathways
8.3K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
8.3K

