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Transabdominal chorionic villus sampling in the second trimester.

C K Hogdall1, T A Doran, J Shime

  • 1Department of Obstetrics and Gynecology, Toronto General Hospital, Ontario, Canada.

American Journal of Obstetrics and Gynecology
|February 1, 1988
PubMed
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Transabdominal chorionic villus sampling using a 17/19 needle combination yielded adequate tissue samples for prenatal genetic diagnosis. This ultrasound-guided second-trimester procedure is effective for high-risk pregnancies.

Area of Science:

  • Medical Science
  • Genetics
  • Obstetrics

Background:

  • Prenatal diagnosis is crucial for managing high-risk pregnancies.
  • Second-trimester genetic testing options are vital for timely intervention.

Purpose of the Study:

  • To evaluate the efficacy of transabdominal chorionic villus sampling (CVS) in the second trimester.
  • To determine optimal needle size for adequate tissue acquisition during CVS.

Main Methods:

  • Ultrasound-guided transabdominal chorionic villus sampling was performed on 19 patients.
  • Various needle size combinations were assessed for tissue sample adequacy.

Main Results:

  • The 17/19 needle size combination consistently provided adequate tissue samples.

Related Experiment Videos

  • Transabdominal CVS proved effective in obtaining sufficient tissue for analysis.

    • Conclusions:

    • Transabdominal chorionic villus sampling is a viable method for second-trimester prenatal genetic diagnosis.
    • The 17/19 needle size is recommended for optimal results in transabdominal CVS.