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Induction of Experimental Autoimmune Hypophysitis in SJL Mice
Published on: December 17, 2010
Autoimmune hypophysitis and viral infection in a pregnant woman: a challengeable case
1Department of Ophthalmology, University Hospital of Medenine, Faculty of Medicine, Sfax University, Tunisia.
Abstract:
The aim of this study is to report a challengeable and rare case of autoimmune hypophysitis possibly induced by viral infections. A young pregnant female developed optic neuropathy due to enlarged sellar mass responsible for hypopituitarism. Investigations exclude neoplasia and systemic diseases. High level of sedimentation rate and magnetic resonance imaging (MRI) findings supported the diagnosis of autoimmune hypophysitis. The patient reported a history of bronchitis treated with antibiotics and corticosteroids and positive serologies for hepatitis B antigen (Hbs antigen), herpes simplex 1 and rubella. Final examination showed complete recovery of visual function and sellar archnoidocele after antiviral treatment and mild dose of corticosteroids.
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