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Clinical features of hemichoreahemiballism: A stroke-related movement disorder

Nobuko Shiraiwa1,2, Sachiko Hoshino2, Go Saito3

  • 1Course of Neurology, Department of Health Sciences, Tsukuba University of Technology.

Neurology International
|August 11, 2020
PubMed

We examined pathogenesis and clinical features of three hemichorea-hemiballism (HCHB) cases. We studied their age, magnetic resonance imaging results, vascular risk factors, management, and outcomes. One man and two women (aged 74-86 years) demonstrated acute onset of HCHB, lasting for at least several months. Patients had one or more vascular risk factors, including hypertension and diabetes. All patients presented subacute or old infarction in the basal ganglia with contralateral symptoms. We administered clonazepam (0.5-1 mg/day), haloperidol (0.375-0.75 mg/day), or both as necessary and observed symptom-control. Vascular lesions in the basal ganglia were a contributing factor. Symptoms were controlled using pharmacotherapy with gamma-aminobutyric acid-agonist (clonazepam) or anti-dopaminergic (haloperidol) medication.

Keywords:
Hemichorea-hemiballismStrokerelated movement disordersbasal ganglia

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