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Related Experiment Video

Updated: Dec 12, 2025

Establishing a Porcine Ex Vivo Cornea Model for Studying Drug Treatments against Bacterial Keratitis
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Parasitic keratitis - An under-reported entity.

Sumeeta Khurana1, Megha Sharma1

  • 1Department of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Tropical Parasitology
|August 11, 2020
PubMed
Summary
This summary is machine-generated.

Parasitic keratitis (PK) is an emerging corneal infection often missed due to its varied presentation. Early diagnosis and management are crucial as parasitic keratitis cases are increasing.

Keywords:
AcanthamoebaMicrosporidiaOnchocercadiagnosing keratitisocular parasites

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Parasitology

Background:

  • Parasitic keratitis (PK) involves corneal inflammation from direct parasitic invasion, endogenous spread, or immune responses.
  • Commonly caused by Acanthamoeba spp. and Microsporidia spp., PK can mimic other corneal conditions, delaying diagnosis.

Purpose of the Study:

  • This review aims to summarize the primary causes of parasitic keratitis.
  • It details the epidemiology, clinical presentation, and microbiology of each causative agent.

Main Methods:

  • A comprehensive literature review was conducted.
  • Information on epidemiological, clinical, and microbiological aspects of parasitic keratitis was synthesized.

Main Results:

  • Parasitic keratitis is caused by various agents, with Acanthamoeba and Microsporidia being most frequent.
  • PK often presents atypically, resembling other infectious and non-infectious keratitis, leading to diagnostic challenges.

Conclusions:

  • Parasitic keratitis is an increasing concern in ophthalmology.
  • A high index of clinical suspicion and appropriate investigations are essential for timely diagnosis and management of PK.